SOC 31-9092 · Louisville/Jefferson County, KY-IN metro

Medical Assistants Salary in Louisville, KY

The average salary for medical assistants in Louisville, Kentucky is $43,680 a year ($21.00 an hour), according to BLS estimates for May 2025. The median is $44,450: half of the 4,140 people in this job in the Louisville/Jefferson County, KY-IN metro area earn more than that, half earn less. That average is 5% less than the U.S. average for this job ($46,120).

$43,680average per year

$21.00 / hourMedian $44,450Take-home ≈ $34,905

  • $37K10th
  • $38K25th
  • $44KMedian
  • $47K75th
  • $50K90th

median average · bar = middle 50% of workers · how to read it

4,140people in this job
-5%vs U.S. average
#1 of 6Kentucky metros
93cost of living (U.S. = 100)
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Medical Assistants pay range in Louisville

New workers and the lowest-paid 10% earn about $37,280 a year or less, while the top 10% make $49,940 or more. The middle half of medical assistants in Louisville earn between $38,490 and $47,420.

  • $37K10th
  • $38K25th
  • $44KMedian
  • $47K75th
  • $50K90th

median average · bar = middle 50% of workers · how to read it

Pay levelPer yearPer monthPer hour*
Average$43,680$3,640$21.00
Median$44,450$3,704$21.37
Entry level (25th percentile)$38,490$3,208$18.50
Experienced (75th percentile)$47,420$3,952$22.80

*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.

Medical Assistants pay in Louisville vs. Kentucky and the U.S.

Medical assistants in Louisville earn 7% more than the Kentucky average ($40,940) and 5% less than the U.S. average ($46,120). At the median the gap is -3% against the U.S. median of $45,690.

AreaAverageMedian10th pct.90th pct.Jobs
Louisville$43,680$44,450$37,280$49,9404,140
Kentucky$40,940$39,270$32,950$47,94013,440
United States$46,120$45,690$36,050$59,310817,870

State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.

Medical Assistants salary after taxes in Louisville

On the average salary of $43,680, a single filer in Louisville takes home about $34,905 a year, or $2,909 a month and $1,342 every two weeks. Taxes take 20% of gross pay.

The Louisville/Jefferson County, KY-IN metro area crosses state lines, so take-home pay depends on the state where you work:

StatePer yearPer month
Working in IN$35,996$3,000
Working in KY$34,905$2,909

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Includes Louisville's local income tax (2.2%).

Kentucky paycheck calculator: try your own salary

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Is Louisville a good place for medical assistants? Pay vs. cost of living

Prices in the Louisville area are 7% below the U.S. average (BEA price parity 93.1), so the average $43,680 buys what about $46,930 would buy in a typical U.S. metro. This job pays 0.9 times the median wage of all jobs in Louisville ($48,370). A typical home costs $283,232, or 6.5 years of this average salary before tax.

See what $43,680 is worth in another city

Medical Assistants salary in other Kentucky cities

Louisville ranks 1st of 6 Kentucky metro areas for this job, the best-paid in the state.

All Medical Assistants salaries in Kentucky

Highest-paying cities for medical assistants

Vallejo, CA pays this job the most of the metro areas we cover ($66,730).

Medical Assistants salary by city

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Reviewed before it counts. Medical Assistants in Louisville, KY.

Medical Assistants salary in Louisville: questions

How much do medical assistants make an hour in Louisville?

$21.00 an hour on average, and $21.37 at the median (BLS, May 2025).

What is the entry-level medical assistants salary in Louisville?

The lowest-paid 10% earn about $37,280 a year and the 25th percentile is $38,490, a fair guide to starting pay.

What is the medical assistants take-home pay in Louisville?

About $34,905 a year ($2,909 a month) for a single filer on the average salary of $43,680. Includes Louisville's local income tax (2.2%).

Do medical assistants earn more in Louisville than elsewhere?

The average here is 5% less than the U.S. average for this job ($46,120).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 31-9092; area Louisville/Jefferson County, KY-IN (31140). Relative standard error of the mean wage: 0.7%.
  • U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Includes Louisville's local income tax (2.2%).
  • Job concentration: location quotient 1.15, this job is about as common as in the U.S. overall.

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