Nurse Practitioners pay range in Louisville
New workers and the lowest-paid 10% earn about $104,090 a year or less, while the top 10% make $159,860 or more. The middle half of nurse practitioners in Louisville earn between $107,220 and $137,830.
- $104K10th
- $107K25th
- $123KMedian
- $138K75th
- $160K90th
median average · bar = middle 50% of workers · how to read it
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $126,690 | $10,558 | $60.91 |
| Median | $122,900 | $10,242 | $59.09 |
| Entry level (25th percentile) | $107,220 | $8,935 | $51.55 |
| Experienced (75th percentile) | $137,830 | $11,486 | $66.26 |
*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.
Nurse Practitioners pay in Louisville vs. Kentucky and the U.S.
Nurse practitioners in Louisville earn about the same as the Kentucky average ($125,010) and 8% less than the U.S. average ($137,300). At the median the gap is -7% against the U.S. median of $132,300.
| Area | Average | Median | 10th pct. | 90th pct. | Jobs |
|---|---|---|---|---|---|
| Louisville | $126,690 | $122,900 | $104,090 | $159,860 | 1,580 |
| Kentucky | $125,010 | $122,870 | $95,710 | $162,960 | 4,770 |
| United States | $137,300 | $132,300 | $101,340 | $174,420 | 323,040 |
State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.
Nurse Practitioners salary after taxes in Louisville
On the average salary of $126,690, a single filer in Louisville takes home about $90,755 a year, or $7,563 a month and $3,491 every two weeks. Taxes take 28% of gross pay.
The Louisville/Jefferson County, KY-IN metro area crosses state lines, so take-home pay depends on the state where you work:
| State | Per year | Per month |
|---|---|---|
| Working in IN | $94,088 | $7,841 |
| Working in KY | $90,755 | $7,563 |
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Includes Louisville's local income tax (2.2%).
Is Louisville a good place for nurse practitioners? Pay vs. cost of living
Prices in the Louisville area are 7% below the U.S. average (BEA price parity 93.1), so the average $126,690 buys what about $136,117 would buy in a typical U.S. metro. This job pays 2.5 times the median wage of all jobs in Louisville ($48,370). A typical home costs $283,232, or 2.2 years of this average salary before tax.
Nurse Practitioners salary in other Kentucky cities
Louisville ranks 3rd of 6 Kentucky metro areas for this job; Owensboro pays the most ($129,790).
- Owensboro$129,790
- Lexington$127,400
- Louisville$126,690
- Paducah$122,990
- Elizabethtown$120,500
- Bowling Green$120,120
Highest-paying cities for nurse practitioners
San Jose, CA pays this job the most of the metro areas we cover ($225,610).
- San Jose, CA$225,610
- San Francisco, CA$215,430
- Vallejo, CA$196,780
- Napa, CA$188,720
- Modesto, CA$187,690
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Nurse Practitioners salary in Louisville: questions
How much do nurse practitioners make an hour in Louisville?
$60.91 an hour on average, and $59.09 at the median (BLS, May 2025).
What is the entry-level nurse practitioners salary in Louisville?
The lowest-paid 10% earn about $104,090 a year and the 25th percentile is $107,220, a fair guide to starting pay.
What is the nurse practitioners take-home pay in Louisville?
About $90,755 a year ($7,563 a month) for a single filer on the average salary of $126,690. Includes Louisville's local income tax (2.2%).
Do nurse practitioners earn more in Louisville than elsewhere?
The average here is 8% less than the U.S. average for this job ($137,300).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1171; area Louisville/Jefferson County, KY-IN (31140). Relative standard error of the mean wage: 2.3%.
- U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Includes Louisville's local income tax (2.2%).
- Job concentration: location quotient 1.11, this job is about as common as in the U.S. overall.
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