Nurse Practitioners Salary in Minnesota

Nurse practitioners in Minnesota earn the most in Mankato (average $145,440 a year) and the least in Rochester ($119,980), across the 5 Minnesota metro areas we cover. Statewide, BLS puts the nurse practitioners average at $135,890 and the median at $133,260 for 7,780 workers. The U.S. average for this job is $137,300.

Nurse Practitioners average salary by city in Minnesota

Mankato$145,440
Duluth$140,360
Minneapolis$137,660
St. Cloud$132,370
Rochester$119,980

Pay, take-home pay and cost of living

City	Average	Median	25th pct.	Take-home*	Cost of living
Mankato	$145,440	$138,580	$133,680	$102,090	91
Duluth	$140,360	$136,530	$125,260	$99,017	89
Minneapolis	$137,660	$133,370	$127,970	$97,383	105
St. Cloud	$132,370	$131,520	$113,660	$94,183	88
Rochester	$119,980	$126,270	$105,820	$86,601	91

*Average salary after federal and state taxes for a single filer; Minnesota Paid Leave premiums are not included. Cost of living: BEA price parity, U.S. = 100.

Nurse Practitioners salary in other states

Nurse Practitioners salary by city and state

More about pay in Minnesota

Sources and how to read this page

Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1171.
U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.

Read the full methodology. Spotted an error? Tell us.