Medical Assistants pay range in Sioux Falls
New workers and the lowest-paid 10% earn about $36,700 a year or less, while the top 10% make $49,540 or more. The middle half of medical assistants in Sioux Falls earn between $38,380 and $46,700.
- $37K10th
- $38K25th
- $44KMedian
- $47K75th
- $50K90th
median average · bar = middle 50% of workers · how to read it
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $43,390 | $3,616 | $20.86 |
| Median | $43,760 | $3,647 | $21.04 |
| Entry level (25th percentile) | $38,380 | $3,198 | $18.45 |
| Experienced (75th percentile) | $46,700 | $3,892 | $22.45 |
*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.
Medical Assistants pay in Sioux Falls vs. South Dakota and the U.S.
Medical assistants in Sioux Falls earn about the same as the South Dakota average ($42,170) and 6% less than the U.S. average ($46,120). At the median the gap is -4% against the U.S. median of $45,690.
| Area | Average | Median | 10th pct. | 90th pct. | Jobs |
|---|---|---|---|---|---|
| Sioux Falls | $43,390 | $43,760 | $36,700 | $49,540 | 620 |
| South Dakota | $42,170 | $41,870 | $35,980 | $48,960 | 1,340 |
| United States | $46,120 | $45,690 | $36,050 | $59,310 | 817,870 |
State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.
Medical Assistants salary after taxes in Sioux Falls
On the average salary of $43,390, a single filer in Sioux Falls takes home about $37,044 a year, or $3,087 a month and $1,425 every two weeks. Taxes take 15% of gross pay.
The Sioux Falls, SD-MN metro area crosses state lines, so take-home pay depends on the state where you work:
| State | Per year | Per month |
|---|---|---|
| Working in SD | $37,044 | $3,087 |
| Working in MN | $35,541 | $2,962 |
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and no state income tax.
Is Sioux Falls a good place for medical assistants? Pay vs. cost of living
Prices in the Sioux Falls area are 9% below the U.S. average (BEA price parity 90.6), so the average $43,390 buys what about $47,875 would buy in a typical U.S. metro. This job pays 0.9 times the median wage of all jobs in Sioux Falls ($47,970). A typical home costs $342,936, or 7.9 years of this average salary before tax.
Medical Assistants salary in other South Dakota cities
Sioux Falls ranks 1st of 2 South Dakota metro areas for this job, the best-paid in the state.
- Sioux Falls$43,390
- Rapid City$41,390
Highest-paying cities for medical assistants
Vallejo, CA pays this job the most of the metro areas we cover ($66,730).
- Vallejo, CA$66,730
- San Jose, CA$65,360
- Santa Rosa, CA$64,160
- San Francisco, CA$63,330
- Napa, CA$62,580
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Medical Assistants salary in Sioux Falls: questions
How much do medical assistants make an hour in Sioux Falls?
$20.86 an hour on average, and $21.04 at the median (BLS, May 2025).
What is the entry-level medical assistants salary in Sioux Falls?
The lowest-paid 10% earn about $36,700 a year and the 25th percentile is $38,380, a fair guide to starting pay.
What is the medical assistants take-home pay in Sioux Falls?
About $37,044 a year ($3,087 a month) for a single filer on the average salary of $43,390. South Dakota has no state income tax.
Do medical assistants earn more in Sioux Falls than elsewhere?
The average here is 6% less than the U.S. average for this job ($46,120).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 31-9092; area Sioux Falls, SD-MN (43620). Relative standard error of the mean wage: 1.2%.
- U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and no state income tax.
- Job concentration: location quotient 0.66, this job is less common than in the U.S. overall (location quotient 0.66).
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