Registered Nurses pay range in Sioux Falls
New workers and the lowest-paid 10% earn about $54,040 a year or less, while the top 10% make $97,330 or more. The middle half of registered nurses in Sioux Falls earn between $65,070 and $81,690.
- $54K10th
- $65K25th
- $75KMedian
- $82K75th
- $97K90th
median average · bar = middle 50% of workers · how to read it
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $74,700 | $6,225 | $35.91 |
| Median | $75,350 | $6,279 | $36.23 |
| Entry level (25th percentile) | $65,070 | $5,422 | $31.28 |
| Experienced (75th percentile) | $81,690 | $6,808 | $39.27 |
*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.
Registered Nurses pay in Sioux Falls vs. South Dakota and the U.S.
Registered nurses in Sioux Falls earn 3% less than the South Dakota average ($77,140) and 26% less than the U.S. average ($101,420). At the median the gap is -23% against the U.S. median of $97,550.
| Area | Average | Median | 10th pct. | 90th pct. | Jobs |
|---|---|---|---|---|---|
| Sioux Falls | $74,700 | $75,350 | $54,040 | $97,330 | 7,680 |
| South Dakota | $77,140 | $78,060 | $54,040 | $98,220 | 14,710 |
| United States | $101,420 | $97,550 | $68,940 | $137,470 | 3,379,720 |
State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.
Registered Nurses salary after taxes in Sioux Falls
On the average salary of $74,700, a single filer in Sioux Falls takes home about $61,381 a year, or $5,115 a month and $2,361 every two weeks. Taxes take 18% of gross pay.
The Sioux Falls, SD-MN metro area crosses state lines, so take-home pay depends on the state where you work:
| State | Per year | Per month |
|---|---|---|
| Working in SD | $61,381 | $5,115 |
| Working in MN | $57,825 | $4,819 |
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and no state income tax.
Is Sioux Falls a good place for registered nurses? Pay vs. cost of living
Prices in the Sioux Falls area are 9% below the U.S. average (BEA price parity 90.6), so the average $74,700 buys what about $82,422 would buy in a typical U.S. metro. This job pays 1.6 times the median wage of all jobs in Sioux Falls ($47,970). A typical home costs $342,936, or 4.6 years of this average salary before tax.
Registered Nurses salary in other South Dakota cities
Sioux Falls ranks 2nd of 2 South Dakota metro areas for this job; Rapid City pays the most ($84,070).
- Rapid City$84,070
- Sioux Falls$74,700
Highest-paying cities for registered nurses
San Jose, CA pays this job the most of the metro areas we cover ($194,950).
- San Jose, CA$194,950
- Vallejo, CA$182,820
- San Francisco, CA$176,900
- Santa Rosa, CA$170,000
- Sacramento, CA$164,200
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Registered Nurses salary in Sioux Falls: questions
How much do registered nurses make an hour in Sioux Falls?
$35.92 an hour on average, and $36.23 at the median (BLS, May 2025).
What is the entry-level registered nurses salary in Sioux Falls?
The lowest-paid 10% earn about $54,040 a year and the 25th percentile is $65,070, a fair guide to starting pay.
What is the registered nurses take-home pay in Sioux Falls?
About $61,381 a year ($5,115 a month) for a single filer on the average salary of $74,700. South Dakota has no state income tax.
Do registered nurses earn more in Sioux Falls than elsewhere?
The average here is 26% less than the U.S. average for this job ($101,420).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1141; area Sioux Falls, SD-MN (43620). Relative standard error of the mean wage: 0.3%.
- U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and no state income tax.
- Job concentration: location quotient 1.98, this job is 2.0 times as concentrated as in the U.S. overall.
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